RESPIRATION
IMPORTANT TERMS
·
Aerobic Respiration: Oxidation of complex organic
molecules in presence of oxygen with CO2, water and energy.
·
Anaerobic Respiration:
Oxidation of complex organic molecules in absence of oxygen to produce ethanol
⁄lactic acid, CO2 and small amount of energy.
·
Amphibolic: A metabolic pathway used in both
catabolism and anabolism.
·
ATP Synthetase:
An enzyme complex that catalyses formation of ATP from ADP and inorganic
phosphate.
·
CO2 Compensation
Point: Atmospheric
concentration of CO2 at which photosynthesis just compensates for
respiration.
·
Cytochromes:
Heme proteins serving as electron carriers in respiration, photosynthesis and
other oxidation reduction reactions.
·
Electron Carriers:
Proteins such as flavoproteins or cytochromes that can reversibly gain or lose
electron.
·
Fermentation:
The oxidation of carbohydrates into ethanol and CO2 by certain
microorganisms under anaerobic condition.
·
Glycolysis:
The catabolic pathway by which a molecule of glucose is broken down into two
molecules of pyruvate.
·
Oxidative Phosphorylation:
Synthesis of ATP with the help of energy released by the oxidation of reduced
coenzymes during respiration.
·
Respiratory Quotient:
The ratio of volume of CO2 released to the volume of O2
consumed during respiration.
·
Substrate level Phosphorylation:
Phosphorylation of ATP or some other nucleotide diphosphate directly forms a
metabolite.
ADDITIONAL INFORMATION
·
Dutrochet:
Coined
the term ‘respiration’.
·
Cruick
Shank (1897): Coined the term ‘fermentation’.
·
Kostytchev
(1902): Coined the term ‘anaerobic respiration’.
·
Homofermentive
Fermentation: When only one main product is formed.
·
Heterofermentive
Fermentation: When two or more than
two types of products are formed.
·
Lactic
acid and Heart: Heart muscles have enzyme to convert
lactic acid into pyruvate. During heavy exercise, lactic acid is formed in
large quantities by skeletal muscles. The same is poured into blood. A part of
it is used by heart muscles in order to obtain extra energy for rapid activity.
·
ETC
Poisons: (i) Cynide prevents
transfer of electrons from cytochrome a3 to oxygen (ii) Antimycin prevents electron transport
between cytochrome b and cytochrome c1 (iii) 2:4 Dinitrophenol allows electron transport but prevents ATP
synthesis.
·
Proton
and ATP synthesis: According to modern physiologists, the
number of protons transported to cytosolic side of inner mitochondrial membrane
is 10 per electron pair from NADH (4+2+4)
and 6 per electron pair from FADH2 (2
+4). Three protons are used up for synthesis of one ATP. However, one proton is
required for transport of each NADH is 2.5 and for each FADH2 as
1.5. The total number of ATP molecules produced per glucose molecule is then 30
or 32 instead of 36 or 38.
·
Smallest
Motor: It is a biological motor consisting of parts of F0
submit of elementary particle and a stalk that passes into F1
subunit.
·
Pasteur
Effect: It is the reduction in consumption of respiratory
substrate, when the mode of respiration is changed from anaerobic to aerobic.
·
Respirometer:
Instrument used for measuring respiratory quotient as well as rate of
respiration.
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